How embryo and mother come together
Cells-in-Motion supports interdisciplinary research project of Britta Trappmann and Ivan Bedzhov
September 15, 2017
In their Flexible Funds Project, Dr. Britta Trappmann, a biomedical engineer and biologist Dr. Ivan Bedzhov want to observe for the first time the entire process by which mouse embryos are implanted in the uterine wall. They will develop a synthetic tissue model, on the basis of a new kind of hydrogel. By using this material system the researches can individually influence many of the parameters. The hydrogel, for example, can have exactly the same degree of softness as the tissue of the lining of the uterus. In this way, Britta Trappmann and Ivan Bedzhov can follow the process by which the embryo is implanted in the uterine wall, and how the cells of the embryo interact with the mother´s blood vessels. In 49 percent of all miscarriages, human embryos do not manage to settle successfully in the uterine wall. So the process is often decisive for the success or failure of a pregnancy.