Ko K, Araúzo-Bravo MJ, Kim J, Stehling M, Schöler HR.
Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells.
Nat Protoc. 5(5):921, 2010. Epub 2010 Apr 22.
Do JT, Schöler HR.
Cell fusion-induced reprogramming.
Methods Mol Biol 636:179, 2010.
Fernandéz-Taboada E, Moritz S, Zeuschner D, Stehling M, Schöler HR, Salé E, Gentile L.
Smed-SmB, a member of the Lsm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation.
Development 137(7):1055, 2010.
Greber B, Wu G, Bernemann C, Joo JY, Han DW, Ko K, Tapia N, Sabour D, Sterneckert J, Tesar P, Schöler HR.
Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells.
Cell Stem Cell 6: 215-226, 2010.
Ko K, Hübner K, Müller-Keuker J, Schöler HR.
In vitro derivation of germ cells from embryonic stem cells.
Frontiers in Bioscience 15:46, 2010.
Do JT, Han DW, Gentile L, Sobek-Klocke I, Wutz A, Schöler HR.
Reprogramming of Xist against the pluripotent state in fusion hybrids.
J Cell Sci, 122:4122, 2009.
Li W, Zhou H, Abujarour R, Zhu S, Joo JY, Lin T, Hao E, Schöler HR, Hayek A, Ding S.
Generation of human induced pluripotent stem cells in the absence of exogenous Sox2.
Stem Cells, 27(12):2992, 2009.
Do JT, Joo JY, Han DW, Araúzo-Bravo MJ, Kim MJ, Greber B, Zaehres H, Sobek-Klocke I, Chung HM, Schöler
Generation of parthenogenetic iPS cells from parthenogenetic neural stem cells.
Stem Cells, 27(12):2962, 2009.
Haase A, Olmer R, Schwanke K, Wunderlich S, Merkert S, Hess C, Zweigerdt R, Gruh
I, Meyer J, Wagner S, Maier LS, Han DW, Glage S, Miller K, Fischer P, Schöler
HR, Martin U.
Generation of induced pluripotent stem cells from human cord blood.
Cell Stem Cell, 5(4):434, 2009.
Kim JB, Zaehres H, Arauzo-Bravo MJ, Schöler HR.
Generation of induced pluripotent stem cells from neural stem cells
Nature Protocols, 4(10):1464, 2009.
Kriegeskotte C, Cantz T, Haberland J, Zibert A, Haier J, Köhler G, Schöler HR, Schmidt HH, Arlinghaus HF.
Laser secondary neutral mass spectrometry for copper detection in micro-scale biopsies.
J Mass Spectrom, 44(10):1417, 2009.
Kim JB, Greber B, Araúzo-Bravo MJ, Meyer J, Park KI, Zaehres H, Schöler HR.
Direct reprogramming of human neural stem cells by OCT4.
Nature, 461(7264):649, 2009.
Loya K, Eggenschwiler R, Ko K, Sgodda M, André F, Bleidißel M, Schöler HR, Cantz T.
Hepatic differentiation of pluripotent stem cells.
Biol Chem, 390(10):1047, 2009.
Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, Sasse P, Glaser T, Ruau D, Han DW, Greber B, Hausdörfer K, Sebastiano V, Stehling M, Fleischmann BK, Brüstle O, Zenke M, Schöler HR.
Induction of pluripotency in adult unipotent germline stem cells.
Cell Stem Cell, 5(1):87, 2009.
Zeuschner D, Mildner K, Zaehres H, Schöler H.
Induced pluripotent stem cells at nano scale.
Stem Cells Dev, 2009 Jun 15 (Epub ahead of print), doi:10.1089/scd.2009.0159.
Do JT, Schöler HR.
Regulatory circuits underlying pluripotency and reprogramming.
Trends Pharmacol Sci, 30: 296, 2009.
Han DW, Do JT, Araúzo-Bravo MJ, Lee SH, Meissner A, Lee HT, Jaenisch R,
Schöler HR.
Epigenetic hierarchy governing Nestin expression.
Stem Cells 27: 1088, 2009.
Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, Siuzdak G, Schöler HR, Duan L, Ding S.
Generation of induced pluripotent stem cells using recombinant proteins.
Cell Stem Cell 4: 381, 2009.
Saxe JP, Tomilin A, Schöler HR, Plath K, Huang J.
Post-translational regulation of Oct4 transcriptional activity.
PLoS ONE 2009;4(2): e4467. Epub 2009 Feb 16.
Kim JB, Sebastiano V, Wu G, Arauzo-Bravo M, Sasse P, Gentile L, Ko K, Ruau D, Ehrich M, van den Boom D, Meyer J, Hübner K,
Bernemann C, Ortmeier C, Zenke M, Fleischmann B, Zaehres H, Schöler H.
Oct4-induced pluripotency in adult neural stem cells.
Cell 136: 411, 2009.
Shi Y, Desponts C, Do JT, Hahm HS, Schöler HR, Ding S.
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds.
Cell Stem Cell 3: 568, 2008.
Zucchi I, Astigiano S, Bertalot G, Sanzone S, Cocola C, Pelucchi P, Bertoli G, Stehling M, Barbieri O, Albertini A, Schöler HR, Neel BG, Reinbold RA, Dulbecco R.
Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells.
Proc Natl Acad Sci U S A 105: 16940, 2008.
Do JT, Han DW, Gentile L, Sobek-Klocke I, Stehling M, Schöer HR
Enhanced Reprogramming of Xist by induced upregulation of Tsix and Dnmt3a.
Stem Cells, 26(11):2821, 2008.
Schöler HR. Commentary:
highlight on stem cell research.
Biol Chem 389: 789, 2008.
Cantz T, Bleidissel M, Stehling M, Schöler HR
In vitro differentiation of reprogrammed murine somatic cells into hepatic precursor cells.
Biol Chem 389: 889, 2008.
Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Arauzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR.
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors.
Nature 454: 646, 2008.
Shi Y, Do JT, Desponts C, Hahm HS, Schöler HR, Ding S.
A combined chemical and genetic approach for the generation of induced pluripotent stem cells.
Cell Stem Cell 2: 525, 2008.
Sharma AD, Cantz T, Vogel A, Schambach A, Haridass D, Iken M, Bleidissel M, Manns MP, Schöler HR, Ott M.
Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation.
Cell Transplant 17: 313, 2008.
Struckmann S, Araúzo-Bravo MJ, Schöler HR, Reinbold RA, Fuellen G.
ReXSpecies--a tool for the analysis of the evolution of gene regulation across species.
BMC Evol Biol 8: 111, 2008.
Han DW, Im YB, Do JT, Gupta MK, Uhm SJ, Kim JH, Schöler HR, Lee HT.
Methylation status of putative differentially methylated regions of porcine IGF2 and H19.
Mol Reprod Dev. 75: 777, 2008.
Han DW, Do JT, Gentile L, Stehling M, Lee HT, Schöler HR.
Pluripotential reprogramming of the somatic genome in hybrid cells occurs with the first cell cycle.
Stem Cells. 26: 445, 2008.
Cavaleri FM, Balbach ST, Gentile L, Jauch A, Böhm-Steuer B, Han YM, Schöler H, Boiani M
Subsets of cloned mouse embryos and their non-random relationship to development and nuclear reprogramming.
Mech. Dev 25: 153, 2008
Graumann J, Nina C. Hübner K, Kim JB, Ko K, Moser M, Kumar C, Cox J, Schöler H, Mann M
SILAC-labeling and proteome quantitation of mouse embryonic stem cells to a depth of 5111 proteins
Mol Cell Proteomics 7: 627, 2008
Cantz T, Key G, Bleidissel M, Gentile L, Han DW, Brenne A, Schöler HR.
Absence of OCT4 Expression in Somatic Tumor Cell Lines.
Stem Cells. 26: 692, 2008.
Zaehres H, Schöler H
Induction of Pluripotency: From Mouse to Human
Cell 131: 834, 2007.
Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, Gokhale S, Schöler HR, Tomilin A, Jaenisch R.
Oct4 expression is not required for mouse somatic stem cell self-renewal.
Cell Stem Cell 1: 403, 2007
Wei F, Schöler HR, Atchison ML.
Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation.
J Biol Chem. 282:21551, 2007.
Blaschke RJ, Hahurij ND, Kuijper S, Just S, Wisse LJ, Deissler K, Maxelon T,
Anastassiadis K, Spitzer J, Hardt SE, Schöler H, Feitsma H, Rottbauer W, Blum M,
Meijlink F, Rappold G, Gittenberger-de Groot AC.
Targeted Mutation Reveals Essential Functions of the Homeodomain Transcription
Factor Shox2 in Sinoatrial and Pacemaking Development.
Circulation. 115: 1830, 2007.
Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK,
Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, Nakatsuji N,
Racowsky C, Rooke H, Rossant J, Schöler HR, Solbakk JH, Taylor P, Trounson AO,
Weissman IL, Wilmut I, Yu J, Zoloth L.
Ethics. The ISSCR guidelines for human embryonic stem cell research.
Science 315: 603, 2007.
Do JT, Han DW, Gentile L, Sobek-Klocke I, Stehling M, Lee HT, Schöler HR.
Erasure of cellular memory by fusion with pluripotent cells.
Stem Cells. 25: 1013, 2007.
Do JT, Han DW, Schöler HR.
Reprogramming somatic gene activity by fusion with pluripotent cells.
Stem Cell Rev. 2(4): 257, 2006.
Hübner K, Kehler J, Schöler HR.
Oocytes.
Methods Enzymol. 418:284, 2006.
Ko K, Schöler HR.
Embryonic stem cells as a potential source of gametes.
Semin Reprod Med. i24: 322, 2006.
Chen S, Do JT, Zhang Q, Yao S, Yan F, Peters EC, Schöler HR, Schultz PG, Ding S.
Self-renewal of embryonic stem cells by a small molecule.
Proc Natl Acad Sci U S A. 103: 17266, 2006.
Kehler J, Hübner K, Schöler HR.
Derivation of germ cells from embryonic stem cells.
Ernst Schering Res Found Workshop. 60: 125, 2006.
Do JT, Schöler HR.
Cell-cell fusion as a means to establish pluripotency.
Ernst Schering Res Found Workshop. 60: 35, 2006.
Schöler HR, Wu G.
Oocytes originating from skin?
Nat Cell Biol. 8: 313, 2006.
Cavaleri F, Gentile L, Schöler HR, Boiani M.
Recombinant human albumin supports development of somatic cell nuclear transfer embryos in mice: toward the establishment of a chemically defined cloning protocol.
Cloning Stem Cells. 8: 24, 2006.
Ehmcke J, Hübner K, Schöler HR, Schlatt S.
Spermatogonia: origin, physiology and prospects for conservation and manipulation of the male germ line.
Reprod Fertil Dev. 18: 7, 2006.
Tolkunova E, Cavaleri F, Eckardt S, Reinbold R, Christenson LK, Schöler HR, Tomilin A.
The caudal-related protein cdx2 promotes trophoblast differentiation of mouse embryonic stem cells.
Stem Cells 24: 139, 2006.
Boiani M, Schöler HR.
Regulatory networks in embryo-derived pluripotent stem cells.
Nat. Rev. Mol. Cell Biol. 6: 872, 2005.
Kehler J, Hübner K, Garrett S, Schöler HR.
Generating oocytes and sperm from embryonic stem cells.
Semin Reprod Med. 23: 222, 2005.
Boiani M, Gentile L, Gambles VV, Cavaleri FM, Redi CA, Schöler HR.
Variable 'reprogramming' of the pluripotent stem cell marker Oct4 in mouse clones: distinct developmental potentials in different culture environments.
Stem Cells 23: 1089, 2005.
Do JT, Schöler HR.
Comparison of neurosphere cells with cumulus cells after fusion with embryonic stem cells: reprogramming potential.
Reproduction, Fertility and Development 17: 143, 2005.
Kehler J, Tolkunova E, Koschorz B, Pesce M, Gentile L, Boiani M, Lomeli H, Nagy A, McLaughlin KJ, Schöler HR, Tomilin A.
Oct4 is required for primordial germ cell survival.
EMBO Rep 5: 1078, 2004.
Do, JT, Schöler HR.
Nuclei of embryonic stem cells reprogram somatic cells.
Stem Cells. 22: 941, 2004.
Boiani M, Kehler J, Schöler HR.
Activity of the germline-specific Oct4-GFP transgene in normal and clone mouse embryos.
Methods Mol Biol. 254: 1, 2004.
Guo Y, Einhorn L, Kelley M, Hirota K, Yodoi J, Reinbold R, Schöler HR, Ramsey H, Hromas R.
Redox regulation of the embryonic stem cell transcription factor oct-4 by thioredoxin.
Stem Cells 22: 259, 2004.
Pan G, Qin B, Liu N, Schöler HR, Pei D.
Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation.
J Biol Chem. 279: 37013, 2004.
Catena R, Tiveron C, Ronchi A, Porta S, Ferri A, Tatangelo L, Cavallaro M, Favaro R, Ottolenghi S, Reinbold R, Schöler HR, Nicolis SK.
Conserved POU-binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.
J Biol Chem. 279: 41846, 2004.
Boiani M, Gambles V, Schöler HR
ATP levels in clone mouse embryos
Cytogenet Genome Res. 105: 270, 2004.
Reményi A, Schöler HR, Wilmanns M.
Combinatorial control of gene expression.
Nat Struct Mol Biol. 11: 812, 2004.
Boiani M, Eckardt S, Leu NA, Schöler HR, McLaughlin KJ.
Pluripotency deficit in clones overcome by clone-clone aggregation: epigenetic complementation?
EMBO J. 22: 5304, 2003.
Reményi, A, Lins, K, Reinbold, R, Schöler HR, Wilmanns M.
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers.
Genes Dev. 17: 2048, 2003.
Parfenov VN, Pochukalina GN, Davis DS, Reinbold R, Schöler HR, Murti KG.
Nuclear distribution of Oct-4 transcription factor in transcriptionally active and inactive mouse oocytes and its relation to RNA polymerase II and splicing factors.
J Cell Biochem 89: 720, 2003.
Ohbo K, Yoshida S, Ohmura M, Ohneda O, Ogawa T, Tsuchiya H, Kuwana T, Kehler J, Abe K, Schöler HR, Suda T.
Identification and characterization of stem cells in prepubertal spermatogenesis in mice small star, filled.
Dev Biol 258: 209, 2003.
Hübner, K., Fuhrmann, G, Christenson, LK, James Kehler, Reinbold, R, De La Fuente, R, Wood, J, Strauss, III, J, Boiani, M, Schöler, HR.
Mouse embryonic stem cells in culture give rise to oocytes.
Science: 300, 1251, 2003.
Lins, K, Reményi, A, Tomilin, A, Massa, S, Wilmanns, M, Matthias, P., Schöler, HR
OBF1 enhances transcriptional potential of Oct1.
EMBO J. 22: 2188, 2003.
Schlatt, S, Honaramooz, A, Boiani, M, Schöler, HR and Dobrinski, I
Progeny from sperm obtained after ectopic grafting of neonatal mouse testes.
Biology of Reproduction 68: 2331, 2003.
Cavaleri F, Schöler HR.
Nanog: a new recruit to the embryonic stem cell orchestra.
Cell 113: 551, 2003.
Anastassiadis, K, Kim, J, Daigle, N, Sprengel, R, Schöler, HR, Stewart, AF.
A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture
Gene 298: 159, 2002.
Honaramooz A, Snedaker A, Boiani M. Schöler HR, Dobrinski I, Schlatt S.
Developmental potential of testis grafts: sperm from neonates.
Nature 418: 778, 2002.
Perspectives article on Boiani et al. (2002) by Solter D.
Cloning v. Clowning.
Genes Dev 16: 1163, 2002.
Boiani M, Eckardt S, Schöler HR, McLaughlin KJ.
Oct4 distribution and level in mouse clones: consequences for pluripotency.
Genes Dev 16: 1209, 2002.
Guo, Y, Costa, R, Ramsey, H, Starnes, T, Vance, G, Robertson, K, Kelley, M, Reinbold, R, Schöler, HR, Hromas, R.
The embryonic stem cell transcription factors Oct-4 and FoxD3/Genesis interact to regulate endodermal-specific promoter expression.
Proc Natl Acad Sci USA 99: 3663, 2002.
Pan, GJ, Chang, ZY, Schöler HR, Pei, DQ.
Stem cell pluripotency and transcription factor Oct-4
Cell Research 12: 319, 2002.
Reményi A, Tomilin A, Schöler HR, Wilmanns M.
Differential Activity by DNA-induced Quarternary Structures of POU Transcription Factors
Biochemical Pharmacology 64: 979, 2002.
Reményi A, Tomilin A, Pohl E, Lins K, Philippsen A, Reinbold R, Schöler HR, Wilmanns M.
Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping.
Mol Cell 8: 569, 2001.
News and Views article on Fuhrmann et al. Dev Cell (2001) by Donovan PJ.
High Oct-ane fuel powers the stem cell.
Nat Genet 29: 246, 2001.
Fuhrmann G, Chung AC, Jackson KJ, Hummelke G, Baniahmad A, Sutter J, Sylvester I, Schöler HR, Cooney AJ.
Mouse germline restriction of Oct4 expression by germ cell nuclear factor.
Dev Cell 1: 377, 2001.
Reményi A, Pohl E, Schöler HR, Wilmanns M.
Crystallization of redox-insensitive Oct1 POU domain with different DNA-response elements.
Acta Crystallogr D Biol Crystallogr 57: 1634, 2001.
Ronfani L, Ferraguti M, Croci L, Ovitt CE, Schöler HR, Consalez GG, Bianchi ME.
Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmb2.
Development 128: 1265, 2001.
Nordhoff V, Hübner K, Bauer A, Orlova I, Malapetsa A, Schöler HR.
Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences.
Mamm Genome 12: 309, 2001.
Pesce M, Schöler HR.
Oct-4: gatekeeper in the beginnings of mammalian development.
Stem Cells 19: 217, 2001.
Tomilin A, Reményi A, Lins K, Bak H, Leidel S, Vriend G, Wilmanns M, Schöler HR.
Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration.
Cell 103: 853, 2000.
Voss AK, Thomas T, Petrou P, Anastassiadis K, Schöler H, Gruss P.
Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos.
Development 127: 5449, 2000.
Butteroni C, De Felici M, Schöler HR, Pesce M.
Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins.
J Mol Biol 304: 529, 2000.
Kirchhof N, Carnwath JW, Lemme E, Anastassiadis K, Schöler HR, Niemann H.
Expression pattern of Oct-4 in preimplantation embryos of different species.
Biol Reprod 63: 1698, 2000.
Ambrosetti DC, Schöler HR, Dailey L, Basilico C.
Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer.
J Biol Chem 275: 23387, 2000.
Anderson R, Copeland TK, Schöler HR, Heasman J, Wylie C.
The onset of germ cell migration in the mouse embryo.
Mech Dev 91: 61, 2000.
Pesce M, Schöler HR.
Oct-4: control of totipotency and germline determination.
Mol Reprod Dev 55: 452, 2000.
Yoshimizu Y, Sugiyama N, De Felice M, Yeom YI, Ohbo K, Masuko K, Obinata M, Abe K, Schöler HR, Matsui Y.
Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice.
Dev Growth Differ 41: 675, 1999.
Pesce M, Marin Gomez M, Philipsen S, Schöler HR.
Binding of Sp1 and Sp3 transcription factors to the Oct-4 promoter.
Cell Mol Biol (Noisy-le-Grand) 45: 709, 1999.
Fuhrmann G, Sylvester I, Schöler HR.
Repression of Oct-4 during embryonic cell differentiation correlates with the appearance of TRIF, a transiently induced DNA-binding factor.
Cell Mol Biol (Noisy-le-Grand) 45: 717, 1999.
Angrand PO, Daigle N, van der Hoeven F, Schöler HR, Stewart AF.
Simplified generation of targeting constructs using ET recombination.
Nucleic Acids Res 27: e16, 1999.
Brehm A, Ohbo K, Zwerschke W, Botquin V, Jansen-Dürr P, Schöler HR.
Synergism with germ line transcription factor Oct-4: viral oncoproteins share the ability to mimic a stem cell-specific activity.
Mol Cell Biol 19: 2635, 1999.
Pesce M, Anastassiadis K, Schöler HR.
Oct-4: lessons of totipotency from embryonic stem cells.
Cells Tissues Organs 165: 144, 1999.
Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, Schöler H, Smith A.
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct-4.
Cell 95: 379, 1998.
De Felice M, Ovitt C, Biffali E, Rodriguez-Mallon A, Arra C, Anastassiadis K, Macchia PE, Mattei MG, Mariano A, Schöler H, Macchia V, Di Lauro R.
A mouse model for hereditary thyroid dysgenesis and cleft palate.
Nat Genet 19: 395, 1998.
Pesce M, Wang X, Wolgemuth DJ, Schöler H.
Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation.
Mech Dev 71: 89, 1998.
Botquin V, Hess H, Fuhrmann G, Anastassiadis C, Gross MK, Vriend G, Schöler HR.
New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct4 and Sox-2.
Genes Dev 12: 2073, 1998.
Ovitt CE, Schöler HR.
The molecular biology of Oct-4 in the early mouse embryo.
Mol Hum Reprod 4: 1021, 1998.
Pesce M, Gross MK, Schöler HR.
In line with our ancestors: Oct-4 and the mammalian germ.
BioEssays 20: 722, 1998.
Brehm A, Ovitt CE, Schöler HR.
Oct-4: more than just a POUerful marker of the mammalian germline?
APMIS 106: 114, 1998.
Brehm A, Ohbo K, Schöler HR.
The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain.
Mol Cell Biol 17: 154, 1997.
Bertocchini F, Ovitt CE, Contil A, Barone V, Schöler HR, Bottinelli R, Reggiani C, Sorrentino V.
Requirement of the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.
EMBO J 16: 6956, 1997.
Yeom YI, Fuhrmann G, Ovitt CE, Brehm A, Ohbo K, Gross M, Hübner K, Schöler HR.
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells.
Development 122: 881, 1996.
Minucci S, Botquin V, Yeom YI, Dey A, Sylvester I, Zand DJ, Ohbo K, Ozato K, Schöler HR.
Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.
EMBO J 15: 888, 1996.
Palmieri SL, Peter W, Hess H, Schöler HR.
Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation.
Dev Biol 166: 259, 1994.
Sylvester I, Schöler HR.
Regulation of the Oct-4 gene by nuclear receptors.
Nucleic Acids Res 22: 901, 1994.
Suzuki N, Peter W, Ciesiolka T, Gruss P, Schöler HR.
Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2.
Nucleic Acids Res 21: 245, 1993.
Yeom YI, Ha HS, Balling R, Schöler HR, Artzt K.
Structure, expression and chromosomal location of the Oct-4 gene.
Mech Dev 35: 171, 1991.
Schöler HR, Ciesiolka T, Gruss P.
A nexus between Oct-4 and E1A: implications for gene regulation in early embryonic stem cells.
Cell 66: 291, 1991.
Schöler HR.
Octamania: the POU factors in murine development.
Trends Genet 7: 323, 1991.
Henseling U, Schmidt W, Schöler HR, Gruss P, Hatzopoulos AK.
A transcription factor interacting with the class I gene enhancer is inactive in tumorigenic cell lines which suppress major histocompatibility complex class I genes.
Mol Cell Biol 10: 4100, 1990.
Suzuki N, Rohdewohld H, Neuman T, Gruss P, Schöler HR.
Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain.
EMBO J 9: 3723, 1990.
Schöler HR, Dressler GR, Balling R, Rohdewohld H, Gruss P.
Oct-4: a germline-specific transcription factor mapping to the mouse t-complex.
EMBO J 9: 2185, 1990.
Schöler HR, Ruppert S, Suzuki N, Chowdhury K, Gruss P.
New type of POU domain in germ line-specific protein Oct-4. Cloning and characterization of the germline-specific octamer binding protein Oct-4.
Nature 344: 435, 1990.
Schöler HR, Hatzopoulos AK, Balling R, Suzuki N, Gruss P.
A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct-factor.
EMBO J 8: 2543, 1989.
Schöler HR, Balling R, Hatzopoulos AK, Suzuki N, Gruss P.
Octamer binding proteins confer transcriptional activity in early mouse embryogenesis.
EMBO J 8: 2551, 1989.
Schöler HR, Balling R, Hatzopoulos AK, Suzuki N, Gruss P.
Transcriptional activity of the octamer motif in embryonic stem cells and preimplantation embryos.
Hormones and Cell Regulation 198: 91, 1989.
Bohmann D, Keller W, Dale T, Schöler HR, Tebb G, Mattaj IW.
A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes.
Nature 325: 268, 1987.
Schlokat U, Bohmann D, Schöler HR, Gruss P.
Nuclear factors binding specific sequences within the immunoglobulin enhancer interact differentially with other enhancer elements.
EMBO J 5: 3251, 1986.
Schöler HR, Haslinger A, Heguy A, Holtgreve H, Karin M.
In vivo competition between a metallothionein regulatory element and the SV40 enhancer.
Science 232: 76, 1986.
Schöler HR, Gruss P.
Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors.
EMBO J 4: 3005, 1985.
Schöler HR, Gruss P.
Specific interaction between enhancer-containing molecules and cellular components.
Cell 36: 403, 1984.
Balbach ST, Cavaleri FM, Gentile L, Araúzo-Bravo MJ, Schöler HR,
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Observing and Manipulating Pluripotency in Normal and Cloned Mouse
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In: Baharvand H. ed. Trends in Stem Cell Biology and Technology.
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Cavaleri F, Schöler HR.
Molecular Facets of Pluripotency.
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Boiani M, Schöler HR.
Pluripotency in Normal and Clone Mouse Embryos.
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Boiani M, Schöler HR.
Determinants of pluripotency in mammals.
In: Cibelli, j. Lanza, RP, Campbell, KHS, West M, Principles of Cloning; 2002: 109.
Ovitt CE, Yeom YI, Schöler HR.
Using LacZ as a reporter for transgenic analysis of embryonic gene expression.
In: Cid-Arregui A, Garcia-Carranca A. Microinjection and Transgenesis. Strategies and Protocols;1997: 427.
Schöler HR, Hatzopoulos AK, Schlokat U.
Enhancers and trans-acting factors.
In: Kahl G, ed. Architecture of Eukaryotic Genes. Verlag Chemie, Weilheim;1988: 89.
Chowdhury K, Schöler HR, Gruss P.
SV40 als modellsystem zum studium eukaryontischer genregulation.
In: Blüm N, ed. Molekular- und Zellbiologie. Springer Verlag;1985: 177.
Schöler HR, Schlokat U, Gruss P.
Cell specific factors required for transcriptional enhancement in vitro.
In: Gluzman Y, ed. Cold Current Topics in Molecular Biology: Eukaryotic Transcription: The Role of Cis- and Trans Acting Elements in Initiation. Spring Harbor;1985:101.
Schöler HR, Gruss P.
Competition for cellular factors required for the transcriptional activation of enhancers.
In: Gluzman Y, Shenk T, eds. Current Topics in Molecular Biology: Enhancers and Eukaryotic Gene Expression. Cold Spring Harbor;1983:16.
Kues WA, Carnwath JW, Niemann H, Schöler HR, Paul D.
A vector-based selection system for totipotent porcine cell lines.
Theriogenology 49: 239, 1998.
Peter W, Hübner K, Schöler HR.
Interaction of EC cell specific proteins with transcription factor Oct-4.
J Cell Biochem 17A: 88, 1993.
Hübner K, Kessler C, Schöler HR.
Translation of eukaryotic messenger RNA in cell-free extracts.
Fresenius Z Anal Chem 329: 428, 1988.
Schöler HR, Gruss P.
Enhancers as transcritional control elements.
Hoppe-Seyler�s Z Physiol Chem 365: 214, 1984.
Fiester A, Schöler HR, Caplan A.
Stem cell therapies: time to talk to the animals.
Cloning Stem Cells 6:3, 2004.
Expert contribution to report "On the State of the Science of Stem Cells" as requested by Tommy G. Thompson, Secretary of Health and Human Services, USA.
Schöler HR.
Das Potential von Stammzellen: Ist der Mensch regenerierbar?
In Kosmos, Erde, Leben (2003)
Modified as Article in: Naturwissenschaftliche Rundschau 56, 524 (2003).
Schöler HR.
Das Potential von Stammzellen: Ist der Mensch regenerierbar?
Bundesgesundheitsblatt
Schöler HR.
Das Potential von Stammzellen: Eine Bestandsaufnahme 47: 565, 2004.