Stem Cells and Regeneration


Seebeck F, Maerz M, Meyer AW, Reuter H, Vogg MC, Stehling M, Mildner K, Zeuschner D, Rabert F, and Bartscherer K (2017). Integrins are required for tissue organization and restriction of neurogenesis in regenerating planarians. Development 144, 795-807.

Owlarn S, and Bartscherer K (2016). Go ahead, grow a head! A planarian's guide to anterior regeneration. Regeneration. Doi: 10.1002/reg2.56.

Reuter H, März M, Vogg MC, Eccles D, Grifol-Boldu L, Owlarn S, Wehner D, Adell T, Weidinger G, and Bartscherer K (2015). β-catenin-dependent control of positional information along the AP body axis in planarians involves a Teashirt family member. Cell Rep 10, 253-265.

Hjeij, R., Onoufriadis, A., Watson, C.M., Slagle, C.E., Klena, N., Dougherty, G.W., Kurkowiak, M., Loges, N.T., Diggle, C.P., Morante, N.F.C., Gabriel, G., Lemke, K.L., Li, Y., Pennekamp, P., Menchen, T., Konert, F., Marthin, J.K., Mans, D.A., Letteboer, S.J.F., Werner, C., Burgoyne, T., Westermann, C., Rutman, A., Carr, I.M., O’Callaghan, C., Moya, E., Chung, E.M.K., UK10K Consortium, Sheridan, E., Nielsen, K.G., Roepman, R., Bartscherer, K., Burdine, R.D., Lo, C.W., Omran, H., Mitchison, H.M. (2014). CCDC151 mutations cause Primary Ciliary Dyskinesia by disruption of the Outer Dynein Arm docking complex formation. Am J Hum Genet 95, 257-274.

Almuedo-Castillo, M., Crespo, X., Seebeck, F., Bartscherer, K., Salo, E., and Adell, T. (2014) JNK controls the onset of mitosis in planarian stem cells and triggers apoptotic cell death required for regeneration and remodeling. PLoS Genet, 10, e1004400.

Vogg, M.C., Owlarn, S., Perez Rico, Y.A., Xie, J., Suzuki, Y., Gentile, L., Wu, W., and Bartscherer, K. (2014). Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors. Dev Biol 390, 136-148.

Böser, A., Drexler, H.C.A., Reuter, H., Schmitz, H., Wu, G., Schöler, H.R., Gentile, L., and Bartscherer, K. (2013). SILAC proteomics of planarians identifies Ncoa5 as a conserved component of pluripotent stem cells. Cell Rep 5, 1142-1155.

März, M., Seebeck, F., and Bartscherer, K. (2013). A Pitx transcription factor controls establishment and maintenance of the serotonergic lineage in planarians. Development 140, 4499-4509.

Gross J.C., Chaudhary, V., Bartscherer, K. , and Boutros, M. (2012). Active Wnt proteins are secreted on exosomes. Nature Cell Biol 14, 1036-45.

Sandmann, T., Vogg, M.C., Owlarn, S., Boutros, M., and Bartscherer, K. (2011). The head regeneration transcriptome of the planarian Schmidtea mediterraneaGenome Biol 12(8):R76.

Gentile, L., Cebria, F., and Bartscherer, K. (2011). The planarian flatworm: a model for stem cell biology and nervous system regeneration. Dis Model Mech 4, 12-19.

Buechling, T., Bartscherer, K. , Ohkawara, B., Chaudhary, V., Spirohn, K., Niehrs, N., and Boutros, M. (2010). Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol 20, 1263-1268.

Abril, J.F., Cebria, F., Rodriguez-Esteban, G., Horn, T., Fraguas, S., Calvo, B., Bartscherer, K. , and Salo, E. (2010). Smed454 dataset: unravelling the transcriptome of Schmidtea mediterranea. BMC Genomics 11:731.

Adell, T., Salo, E., Boutros, M., and Bartscherer, K. (2009). Smed-Evi/Wntless is required for beta-catenin-dependent and –independent processes during planarian regeneration. Development 136, 905-910.

Davidson, G., Shen, J., Huang, Y., Su, Y., Karaulanov, E., Bartscherer, K. , Hassler, C., Stannek P., Boutros, M., and Niehrs, C. (2009). Cell Cycle Control of Wnt Receptor Activation. Dev Cell 17, 788-799.

Bartscherer, K. , and Boutros, M. (2008). Regulation of Wnt protein secretion and its role in gradient formation. EMBO Rep 9, 977-982.

Bartscherer, K. , Pelte, N., Ingelfinger, D., and Boutros, M. (2006). Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125, 523-533.


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