Publications

 

Stewen, J, Kruse, K, Godoi-Filip, AT, Zenia, Jeong, HW, Adams, S, Berkenfeld, F, Stehling, M, Red-Horse, K, Adams, RH^#, Pitulescu, ME^# (2024). Eph-ephrin signaling couples endothelial cell sorting and arterial specification. Nature Commun 15:2539, doi: 10.1038/s41467-024-46300-0. ^# Shared corresponding authorship

Xu, C*, Dinh, VV*, Kruse, K, Jeong, H, Watson, EC, Adams, S, Berkenfeld, F, Stehling, M, Rasouli, SJ, Fan, R, Chen, R, Bedzhov, I, Chen, Q, Kato, K, Pitulescu, ME^#, Adams, RH^# (2022). Induction of osteogenesis by bone-targeted Notch activation. Elife, 11, doi: 10.7554/eLife.60183. ^# Shared corresponding authorship.

Luxan, G*, Stewen, J*, Diaz, N, Kato, K, Maney, SK, Aravamudhan, A, Berkenfeld, F, Nagelmann, N, Drexler, HC, Zeuschner, D, Faber, C, Schillers, H, Hermann, S, Wiseman, J, Vaquerizas, JM, Pitulescu, ME^#, Adams, RH^# (2019). Endothelial EphB4 maintains vascular integrity and transport function in adult heart. Elife, 8:e45863, doi: 10.7554/eLife.45863. *, ^# Shared first or corresponding authorship, respectively.

Corada, M, Orsenigo, F, Bhat, GP, Conze, LL, Breviario, F, Cunha, SI, Claesson-Welsh, L, Beznoussenko, GV, Mironov, AA, Bacigaluppi, M, Martino, G, Pitulescu, ME, Adams, RH, Magnusson, P, & Dejana, E (2019). Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier. Circ Res 124(4), 511-525, doi: 10.1161/CIRCRESAHA.118.313316.

Del Monte-Nieto, G, Ramialison, M, Adam, AAS, Wu, B, Aharonov, A, D'Uva, G, Bourke, LM, Pitulescu, ME, Chen, H, de la Pompa, JL, Shou, W, Adams, RH, Harten, SK, Tzahor, E, Zhou, B, & Harvey, RP (2018). Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature, 557(7705), 439-445, doi.org/10.1038/s41586-018-0110-6.

Cao, J, Ehling, M, Marz, S, Seebach, J, Tarbashevich, K, Sixta, T, Pitulescu, ME, Werner, AC, Flach, B, Montanez, E, Raz, E, Adams, RH, & Schnittler, H (2017). Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nat Commun 8(1), 2210, doi.org/10.1038/s41467-017-02373-8

Langen, U, Pitulescu, ME, Kim, JM, Enriquez-Gasca, R, Sivaraj, KK, Kusumbe, AP, Singh, A, Di Russo, J, Bixel, MG, Zhou, B, Sorokin, L, Vaquerizas, JM, & Adams, RH (2017). Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol 19(3), 189-201, doi: 10.1038/ncb3476.

Pitulescu, ME^#, Schmidt, I, Giaimo, BD, Antoine, T, Berkenfeld, F, Ferrante, F, Park, H, Ehling, M, Biljes, D, Rocha, SF, Langen, UH, Stehling, M, Nagasawa, T, Ferrara, N, Borggrefe, T, Adams, RH^#  (2017). Dll4 and Notch signalling couples sprouting angiogenesis and artery formation. Nat Cell Biol 19, 915-927, doi: 10.1038/ncb3555. ^# Co-corresponding authorship.

Shah, AV, Birdsey, GM, Peghaire, C, Pitulescu, ME, Dufton, NP, Yang, Y, Weinberg, I, Osuna Almagro, L, Payne, L, Mason, JC, Gerhardt, H, Adams, RH, & Randi, AM (2017). The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability. Nat Commun, 8, 16002, doi.org/10.1038/ncomms16002.

Nunan, R, Campbell, J, Mori, R, Pitulescu, ME, Jiang, WG, Harding, KG, Adams, RH, Nobes, CD, & Martin, P (2015). Ephrin-Bs Drive Junctional Downregulation and Actin Stress Fiber Disassembly to Enable Wound Re-epithelialization. Cell Rep, 13(7), 1380-1395, doi: 10.1016/j.celrep.2015.09.085.

Ottone, C, Krusche, B, Whitby, A, Clements, M, Quadrato, G, Pitulescu, ME, Adams, RH, & Parrinello, S (2014). Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells. Nat Cell Biol, 16(11), 1045-1056, doi.org/10.1038/ncb3045.

Xu, C, Hasan, SS, Schmidt, I, Rocha, SF, Pitulescu, ME, Bussmann, J, Meyen, D, Raz, E, Adams, RH, & Siekmann, AF (2014). Arteries are formed by vein-derived endothelial tip cells. Nat Commun, 5, 5758, doi: 10.1038/ncomms6758.

Pitulescu, ME & Adams, RH (2014). Regulation of signaling interactions and receptor endocytosis in growing blood vessels. Cell Adh Migr, 8(4), 366-377, doi.org/10.4161/19336918.2014.970010.

Tuoc, TC, Boretius, S, Sansom, SN, Pitulescu, ME, Frahm, J, Livesey, FJ, & Stoykova, A (2013). Chromatin regulation by BAF170 controls cerebral cortical size and thickness. Dev Cell, 25(3), 256-269, doi: 10.1016/j.devcel.2013.04.005.

Corada, M, Orsenigo, F, Morini, MF, Pitulescu, ME, Bhat, G, Nyqvist, D, Breviario, F, Conti, V, Briot, A, Iruela-Arispe, ML, Adams, RH, & Dejana, E (2013). Sox17 is indispensable for acquisition and maintenance of arterial identity. Nat Commun, 4, 2609, doi: 10.1038/ncomms3609.

Pitulescu, ME, & Adams, RH (2010). Eph/ephrin molecules--a hub for signaling and endocytosis. Genes Dev, 24(22), 2480-2492, doi: 10.1101/gad.1973910.

Wang, Y*, Nakayama, M*, Pitulescu, ME*, Schmidt, TS*, Bochenek, ML, Sakakibara, A, Adams, S, Davy, A, Deutsch, U, Luthi, U, Barberis, A, Benjamin, LE, Makinen, T, Nobes, CD, & Adams, RH (2010). Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature, 465(7297), 483-486, doi: 10.1038/nature09002. * Shared first authorship.

Sawamiphak, S, Seidel, S, Essmann, CL, Wilkinson, GA, Pitulescu, ME, Acker, T, & Acker-Palmer, A (2010). Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature, 465(7297), 487-491, doi: 10.1038/nature08995.

Pitulescu, ME^§, Schmidt, I, Benedito, R & Adams, RH (2010). Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice. Nat Protoc, 5(9), 1518-1534, doi: 10.1038/nprot.2010.113. ^§ corresponding author.

Pitulescu, ME, Teichmann, M, Luo, L, & Kessel, M (2009). TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation. BMC Biochem, 10, 16, doi: 10.1186/1471-2091-10-16.

Asli, NS, Pitulescu, ME, & Kessel, M (2008). MicroRNAs in organogenesis and disease. Curr Mol Med 8(8), 698-710, doi: 10.2174/156652408786733739.

Bart, JM, Morariu, S, Knapp, J, Ilie, MS, Pitulescu, M, Anghel, A, Cosoroaba, I, & Piarroux, R (2006). Genetic typing of Echinococcus granulosus in Romania. Parasitol Res, 98(2), 130-137, doi: 10.1007/s00436-005-0015-9.

Pitulescu, M, Kessel, M, & Luo, L (2005). The regulation of embryonic patterning and DNA replication by geminin. Cell Mol Life Sci, 62(13), 1425-1433, https://doi.org/10.1007/s00018-005-4553-1.

Anghel, A, Marian, C, Pitulescu, M, Daba, A, Sirbu, IO, Rusu, V, & Budowle, B (2003). Population genetic study of eight short tandem repeat loci CSF1PO, TPOX, TH01, F13A01, FESFPS, vWA, F13B and LPL in the Western Romanian population. Forensic Sci Int, 131(2-3), 218-219, DOI:10.1016/S0379-0738(02)00435-8.