Blood vessels in the skeletal system control bone formation

Research report (imported) 2014 - Max Planck Institute for Molecular Biomedicine

Kusumbe, Anjali P.; Ramasamy, Saravana K.; Adams, Ralf H.
Abteilung Gewebebiologie und Morphogenese (Adams)

Blood vessels provide the whole organism with essential oxygen and nutrients, but are also an important source of regulatory cues in many organs. In the skeletal system, specialized capillaries release signals that control bone-forming progenitor cells and thereby bone growth. The aging organism lacks such specialized blood vessels and shows a detrimental decline in bone renewal. New results indicate that the stimulation of blood vessel growth in such conditions might be therapeutically beneficial.

For the full text, see the German version.

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