Fingerprints of cancer heterogeneity predict disease outcome

Research report (imported) 2024 - Max Planck Institute for Molecular Biomedicine

Authors
Wickström, Sara
Departments
Abteilung Zell- und Gewebedynamik
Summary
Cancer diagnosis is a major medical challenge because current methods are time-consuming, manual and limited in their accuracy. We have developed an AI-based image analysis approach to analyse tumours and surrounding tissue at single cell resolution. Using patient-specific cellular 'fingerprints', we have shown that the combination of certain features indicates poorer prognosis and resistance to therapy. These results point to new approaches for improved diagnosis and therapy.

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