Recent publications

Hervé S, Scelfo A, Bersano-Marchisio G, Grison M, Vaidziulyte K, Deygas M, Nader G, Mace A-S, Gentili M, Williart A, Manel N, Piel M, Miroshnikova YA* (co-last/co-corresponding), Fachinetti*. Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint. Nat Cell Biol (2025). https://doi.org/10.1038/S41556-024-01565-X

McCreery K, Stubb A, Stephens R, Cook A, Kruse K, Lackmann J, Niessen CM, Biggs LC, Nykänen S, Zou J, Vuoristo S, Miroshnikova YA* (co-last/co-corresponding), and Wickström SA*. Mechano-osmotic signals control chromatin state and exit from pluripotency. (in revision Nat Cell Biol; https://www.biorxiv.org/content/10.1101/2024.09.07.611779v1)

Kaivola J, Punovuori K, Chastney MR, Miroshnikova YA, Abdo H, Bertillot F, Krautgasser F, Di Franco J, Conway JRW, Follain G, Hagström J, Mäkitie A, Irjala H, Ventelä S, Hamidi H, Scita G, Cerbino R, Wickström SA, and Ivaska J. Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer. (in revision Nature Materials https://www.biorxiv.org/content/10.1101/2024.08.22.609159v1)

Punovuori, K., Bertillot, F., Miroshnikova, Y.A., Binner, M.I., Myllymäki, S.M., Follain, G., Kruse, K., Routila, J., Huusko, T., Pellinen, T., et al. (2024). Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer. Cell 187. DOI: https://doi.org/10.1016/J.CELL.2024.09.046.

Bansaccal N, Vieugue P, Sarate R, Song Y, Minguijon E, Miroshnikova YA, Zeuschner D, Collin A, Allard J, Engelman D, Delaunois AL, Liagre M, de Groote L, Timmerman E, Van Haver D, Impens F, Salmon I, Wickström SA, Sifrim A, Blanpain C. The extracellular matrix dictates regional competence for tumour initiation. Nature. 2023. 623(7988):828-835. DOI: 10.1038/s41586-023-06740-y

Stephens KR and Miroshnikova YA. Nuclear periphery and its mechanical regulation in cell fate transitions. Curr Opin Struct Biol. 2024. Jun 17:87:102867. DOI: 10.1016/j.sbi.2024.102867

Hervé S and Miroshnikova YA. Biophysical determinants of nuclear shape and mechanics and their implications for genome integrity. Curr. Opin. Biomed. Eng. 2023. June 2024:30:100521. DOI: 10.1016/j.cobme.2024.100521

Bertillot and Miroshnikova YA (co-first, co-corresponding). SnapShot: Mechanotransduction in the nucleus. Cell. 2022 Sep 15;185(19):3638-3638. DOI: 10.1016/j.cell.2022.08.017

Koester, J., Miroshnikova YA, Ghatak S, Andrés Chacón-Martínez C, Li X, Atanassov I, Altmüller J, Birk DE, Iglesias M, Wickström SA. Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility. Nat Cell Biol. 2021 Jul;23(7):771-781. DOI: 10.1038/s41556-021-00705-x

Miroshnikova YA (co-corresponding), Manet S, Li X, Wickström SA, Faurobert E, Albiges-Rizo C. Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch. Mol Biol Cell. 2021 Aug 19;32(18):1724-1736. DOI: 10.1091/mbc.E21-03-0106

Nava MM and Miroshnikova YA (co-first), Biggs LC, Whitefield DB, Vihinen H, Jokitalo E, García Arcos JM, Hoffmann B, Merkel R, Niessen CM, Noel Dahl K, and Wickström S.A. Heterochromatin-driven nuclear softening protects the genome against mechanical stress-induced damage. Cell 2020 May 14;181(4):800817. DOI: 10.1016/j.cell.2020.03.052

Dekoninck S, Hannezo E , Sifrim A, Miroshnikova YA, Aragona M, Malfait M, Gargouri S , de Neunheuser S, Dubois C, Voet T, Wickström SA, Simons BD, Blanpain C. Defining the Design Principles of Skin Epidermis Postnatal Growth. Cell 2020 Apr 30;181(3):604-620. DOI: 10.1016/j.cell.2020.03.015

Miroshnikova YA, Le HQ, Schneider, D... & Wickström SA. A biomechanical network of adhesion forces and cell mechanics couples proliferation and differentiation to drive epidermal stratification. Nat Cell Biol 2018 Jan;20(1):69-80. DOI: 10.1038/s41556-017-0005-z